Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
نویسندگان
چکیده
منابع مشابه
The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP.
Animal and plant uncoupling protein (UCP) homologues form a subfamily of mitochondrial carriers that are evolutionarily related and possibly derived from a proton/anion transporter ancestor. The brown adipose tissue (BAT) UCP1 has a marked and strongly regulated uncoupling activity, essential to the maintenance of body temperature in small mammals. UCP homologues identified in plants are induce...
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This study has identified the expression of uncoupling proteins in a marsupial using molecular techniques. The Tasmanian bettong, Bettongia gaimardi, increases non-shivering thermogenesis (NST) in response to cold exposure and norepinephrine, although previous studies have been unable to demonstrate the presence of brown adipose tissue or uncoupling protein 1 (UCP1). This study used molecular t...
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Introduction: The effect of regular exercise in decreasing the incidence of heart diseases is well known. The abuse of anabolic androgenic steroids (AAS) has been associated with cardiovascular disorders. Uncoupling proteins (UCPs) transport protons across the inner mitochondrial membrane thereby proton gradient can be diminished by the action of UCPs. This process will result in the uncoupl...
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Proteases play important roles during plant growth and development, activating some proteins, removing targeting peptides, maintaining protein quality control and degrading specific proteins in response to diverse environmental and developmental stimuli. According to the endosymbiontic origin, mitochondria contain their own proteolytic system. The majority of information regarding mitochondrial...
متن کاملRole of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation
BACKGROUND/PURPOSE Major psychiatric illnesses, affecting 36% of the world's population, are profound disorders of thought, mood and behavior associated with underlying impairments in synaptic plasticity and cellular resilience. Mitochondria support energy demanding processes like neural transmission and synaptogenesis and are thus points of broadening interest in the energetics underlying the ...
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ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2005
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2005.06.002